Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection

Efforts to develop an effective vaccine against the hepatitis C virus (HCV; human hepacivirus) have been stymied by a lack of small animal models. Here, we describe an experimental rat model of chronic HCV-related hepacivirus infection and its response to T cell immunization. Immune-competent rats c...

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Detalles Bibliográficos
Autores principales: Hartlage, Alex S., Murthy, Satyapramod, Kumar, Arvind, Trivedi, Sheetal, Dravid, Piyush, Sharma, Himanshu, Walker, Christopher M., Kapoor, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405742/
https://www.ncbi.nlm.nih.gov/pubmed/30846697
http://dx.doi.org/10.1038/s41467-019-09105-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405742/
https://www.ncbi.nlm.nih.gov/pubmed/30846697
http://dx.doi.org/10.1038/s41467-019-09105-0

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