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Chimeric NANOG repressors inhibit glioblastoma growth in vivo in a context-dependent manner

Targeting stemness promises new therapeutic strategies against highly invasive tumors. While a number of approaches are being tested, inhibiting the core transcription regulatory network of cancer stem cells is an attractive yet challenging possibility. Here we have aimed to provide the proof of pri...

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Detalles Bibliográficos
Autores principales: Kuciak, Monika, Mas, Christophe, Borges, Isabel, Sánchez-Gómez, Pilar, Ruiz i Altaba, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405761/
https://www.ncbi.nlm.nih.gov/pubmed/30846719
http://dx.doi.org/10.1038/s41598-019-39473-y