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Chimeric NANOG repressors inhibit glioblastoma growth in vivo in a context-dependent manner
Targeting stemness promises new therapeutic strategies against highly invasive tumors. While a number of approaches are being tested, inhibiting the core transcription regulatory network of cancer stem cells is an attractive yet challenging possibility. Here we have aimed to provide the proof of pri...
Autores principales: | Kuciak, Monika, Mas, Christophe, Borges, Isabel, Sánchez-Gómez, Pilar, Ruiz i Altaba, Ariel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405761/ https://www.ncbi.nlm.nih.gov/pubmed/30846719 http://dx.doi.org/10.1038/s41598-019-39473-y |
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