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The epigenetic basis for the impaired ability of adult murine retinal pigment epithelium cells to regenerate retinal tissue

The epigenetic plasticity of amphibian retinal pigment epithelium (RPE) allows them to regenerate the entire retina, a trait known to be absent in mammals. In this study, we investigated the epigenetic plasticity of adult murine RPE to identify possible mechanisms that prevent mammalian RPE from reg...

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Detalles Bibliográficos
Autores principales: Dvoriantchikova, Galina, Seemungal, Rajeev J., Ivanov, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405859/
https://www.ncbi.nlm.nih.gov/pubmed/30846751
http://dx.doi.org/10.1038/s41598-019-40262-w