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Local resources of polyribosomes and SER promote synapse enlargement and spine clustering after long-term potentiation in adult rat hippocampus

Synapse clustering facilitates circuit integration, learning, and memory. Long-term potentiation (LTP) of mature neurons produces synapse enlargement balanced by fewer spines, raising the question of how clusters form despite this homeostatic regulation of total synaptic weight. Three-dimensional re...

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Detalles Bibliográficos
Autores principales: Chirillo, Michael A., Waters, Mikayla S., Lindsey, Laurence F., Bourne, Jennifer N., Harris, Kristen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405867/
https://www.ncbi.nlm.nih.gov/pubmed/30846859
http://dx.doi.org/10.1038/s41598-019-40520-x