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Local resources of polyribosomes and SER promote synapse enlargement and spine clustering after long-term potentiation in adult rat hippocampus
Synapse clustering facilitates circuit integration, learning, and memory. Long-term potentiation (LTP) of mature neurons produces synapse enlargement balanced by fewer spines, raising the question of how clusters form despite this homeostatic regulation of total synaptic weight. Three-dimensional re...
Autores principales: | Chirillo, Michael A., Waters, Mikayla S., Lindsey, Laurence F., Bourne, Jennifer N., Harris, Kristen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405867/ https://www.ncbi.nlm.nih.gov/pubmed/30846859 http://dx.doi.org/10.1038/s41598-019-40520-x |
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