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Development of a novel short 12-meric papiliocin-derived peptide that is effective against Gram-negative sepsis

The development of novel peptide antibiotics with potent activity against multidrug-resistant Gram-negative bacteria and anti-septic activity is urgently needed. In this study, we designed short, 12-meric antimicrobial peptides by substituting amino acids from the N-terminal 12 residues of the papil...

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Detalles Bibliográficos
Autores principales: Kim, Jieun, Jacob, Binu, Jang, Mihee, Kwak, Chulhee, Lee, Yeongjoon, Son, Kkabi, Lee, Sujin, Jung, In Duk, Jeong, Myeong Seon, Kwon, Seung-Hae, Kim, Yangmee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405874/
https://www.ncbi.nlm.nih.gov/pubmed/30846839
http://dx.doi.org/10.1038/s41598-019-40577-8