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Development of a novel short 12-meric papiliocin-derived peptide that is effective against Gram-negative sepsis
The development of novel peptide antibiotics with potent activity against multidrug-resistant Gram-negative bacteria and anti-septic activity is urgently needed. In this study, we designed short, 12-meric antimicrobial peptides by substituting amino acids from the N-terminal 12 residues of the papil...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405874/ https://www.ncbi.nlm.nih.gov/pubmed/30846839 http://dx.doi.org/10.1038/s41598-019-40577-8 |