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Imaging inflammation using an activated macrophage probe with Slc18b1 as the activation-selective gating target

Activated macrophages have the potential to be ideal targets for imaging inflammation. However, probe selectivity over non-activated macrophages and probe delivery to target tissue have been challenging. Here, we report a small molecule probe specific for activated macrophages, called CDg16, and dem...

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Detalles Bibliográficos
Autores principales: Park, Sung-Jin, Kim, Beomsue, Choi, Sejong, Balasubramaniam, Sivaraman, Lee, Sung-Chan, Lee, Jung Yeol, Kim, Heon Seok, Kim, Jun-Young, Kim, Jong-Jin, Lee, Yong-An, Kang, Nam-Young, Kim, Jin-Soo, Chang, Young-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405920/
https://www.ncbi.nlm.nih.gov/pubmed/30846702
http://dx.doi.org/10.1038/s41467-019-08990-9