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Combined SIRT3 and SIRT5 deletion is associated with inner retinal dysfunction in a mouse model of type 1 diabetes

Diabetic retinopathy (DR) is a major cause of blindness in working adults in the industrialized world. In addition to vision loss caused by macular edema and pathological angiogenesis, DR patients often exhibit neuronal dysfunction on electrophysiological testing, suggesting that there may be an ind...

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Detalles Bibliográficos
Autores principales: Lin, Jonathan B., Lin, Joseph B., Chen, Howard C., Chen, Teresa, Apte, Rajendra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406004/
https://www.ncbi.nlm.nih.gov/pubmed/30846716
http://dx.doi.org/10.1038/s41598-019-40177-6