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Combined SIRT3 and SIRT5 deletion is associated with inner retinal dysfunction in a mouse model of type 1 diabetes
Diabetic retinopathy (DR) is a major cause of blindness in working adults in the industrialized world. In addition to vision loss caused by macular edema and pathological angiogenesis, DR patients often exhibit neuronal dysfunction on electrophysiological testing, suggesting that there may be an ind...
Autores principales: | Lin, Jonathan B., Lin, Joseph B., Chen, Howard C., Chen, Teresa, Apte, Rajendra S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406004/ https://www.ncbi.nlm.nih.gov/pubmed/30846716 http://dx.doi.org/10.1038/s41598-019-40177-6 |
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