Extremely Low Organ Toxicity and Strong Antitumor Activity of miR-34-Regulated Oncolytic Coxsackievirus B3

Oncolytic virotherapies have emerged as new modalities for cancer treatment. We previously reported that coxsackievirus B3 (CVB3) is a novel oncolytic virus (OV) with a strong ability to lyse human non-small cell lung cancer cells; however, its non-specific toxicity against normal cells remains to b...

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Detalles Bibliográficos
Autores principales: Jia, Yang, Miyamoto, Shohei, Soda, Yasushi, Takishima, Yuto, Sagara, Miyako, Liao, Jiyuan, Hirose, Lisa, Hijikata, Yasuki, Miura, Yoshie, Hara, Kenichiro, Iwanaga, Atsufumi, Ota, Yasunori, Tani, Kenzaburo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406029/
https://www.ncbi.nlm.nih.gov/pubmed/30891489
http://dx.doi.org/10.1016/j.omto.2019.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406029/
https://www.ncbi.nlm.nih.gov/pubmed/30891489
http://dx.doi.org/10.1016/j.omto.2019.01.003

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