A bovine CD18 signal peptide variant with increased binding activity to Mannheimia hemolytica leukotoxin

Background: Mannheimia haemolytica is the major bacterial infectious agent of bovine respiratory disease complex and causes severe morbidity and mortality during lung infections. M. haemolytica secretes a protein leukotoxin (Lkt) that binds to the CD18 receptor on leukocytes, initiates lysis, induce...

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Detalles Bibliográficos
Autores principales: Workman, Aspen M., Chitko-McKown, Carol G., Smith, Timothy P. L., Bennett, Gary L., Kalbfleisch, Theodore S., Basnayake, Veronica, Heaton, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406179/
https://www.ncbi.nlm.nih.gov/pubmed/30881690
http://dx.doi.org/10.12688/f1000research.17187.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406179/
https://www.ncbi.nlm.nih.gov/pubmed/30881690
http://dx.doi.org/10.12688/f1000research.17187.1

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