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A bovine CD18 signal peptide variant with increased binding activity to Mannheimia hemolytica leukotoxin
Background: Mannheimia haemolytica is the major bacterial infectious agent of bovine respiratory disease complex and causes severe morbidity and mortality during lung infections. M. haemolytica secretes a protein leukotoxin (Lkt) that binds to the CD18 receptor on leukocytes, initiates lysis, induce...
Autores principales: | Workman, Aspen M., Chitko-McKown, Carol G., Smith, Timothy P. L., Bennett, Gary L., Kalbfleisch, Theodore S., Basnayake, Veronica, Heaton, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406179/ https://www.ncbi.nlm.nih.gov/pubmed/30881690 http://dx.doi.org/10.12688/f1000research.17187.1 |
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