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Hutchinson-Gilford Progeria Syndrome—Current Status and Prospects for Gene Therapy Treatment
Hutchinson-Gilford progeria syndrome (HGPS) is one of the most severe disorders among laminopathies—a heterogeneous group of genetic diseases with a molecular background based on mutations in the LMNA gene and genes coding for interacting proteins. HGPS is characterized by the presence of aging-asso...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406247/ https://www.ncbi.nlm.nih.gov/pubmed/30691039 http://dx.doi.org/10.3390/cells8020088 |