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Hutchinson-Gilford Progeria Syndrome—Current Status and Prospects for Gene Therapy Treatment

Hutchinson-Gilford progeria syndrome (HGPS) is one of the most severe disorders among laminopathies—a heterogeneous group of genetic diseases with a molecular background based on mutations in the LMNA gene and genes coding for interacting proteins. HGPS is characterized by the presence of aging-asso...

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Detalles Bibliográficos
Autores principales: Piekarowicz, Katarzyna, Machowska, Magdalena, Dzianisava, Volha, Rzepecki, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406247/
https://www.ncbi.nlm.nih.gov/pubmed/30691039
http://dx.doi.org/10.3390/cells8020088