Activation of CD8(+) T Cell Responses after Melanoma Antigen Targeting to CD169(+) Antigen Presenting Cells in Mice and Humans

The lack of tumor-reactive T cells is one reason why immune checkpoint inhibitor therapies still fail in a significant proportion of melanoma patients. A vaccination that induces melanoma-specific T cells could potentially enhance the efficacy of immune checkpoint inhibitors. Here, we describe a vac...

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Detalles Bibliográficos
Autores principales: van Dinther, Dieke, Lopez Venegas, Miguel, Veninga, Henrike, Olesek, Katarzyna, Hoogterp, Leoni, Revet, Mirjam, Ambrosini, Martino, Kalay, Hakan, Stöckl, Johannes, van Kooyk, Yvette, den Haan, Joke M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406251/
https://www.ncbi.nlm.nih.gov/pubmed/30764534
http://dx.doi.org/10.3390/cancers11020183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406251/
https://www.ncbi.nlm.nih.gov/pubmed/30764534
http://dx.doi.org/10.3390/cancers11020183

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