Direct Single-Cell Analysis of Human Polar Bodies and Cleavage-Stage Embryos Reveals No Evidence of the Telomere Theory of Reproductive Ageing in Relation to Aneuploidy Generation

Reproductive ageing in women, particularly after the age of 35, is associated with an exponential increase in the proportion of chromosomally abnormal oocytes produced. Several hypotheses have attempted to explain this observation, including the ‘limited oocyte pool’ hypothesis and the ‘two-hit’ hyp...

Descripción completa

Detalles Bibliográficos
Autores principales: Turner, Kara, Lynch, Colleen, Rouse, Hannah, Vasu, Vimal, Griffin, Darren K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406255/
https://www.ncbi.nlm.nih.gov/pubmed/30781491
http://dx.doi.org/10.3390/cells8020163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406255/
https://www.ncbi.nlm.nih.gov/pubmed/30781491
http://dx.doi.org/10.3390/cells8020163

Ejemplares similares