Putative Mechanisms Underlying High Inhibitory Activities of Bimodular DNA Aptamers to Thrombin

Nucleic acid aptamers are prospective molecular recognizing elements. Similar to antibodies, aptamers are capable of providing specific recognition due to their spatial structure. However, the apparent simplicity of oligonucleotide folding is often elusive, as there is a balance between several conf...

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Detalles Bibliográficos
Autores principales: Zavyalova, Elena G., Legatova, Valeriia A., Alieva, Rugiya Sh., Zalevsky, Arthur O., Tashlitsky, Vadim N., Arutyunyan, Alexander M., Kopylov, Alexey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406280/
https://www.ncbi.nlm.nih.gov/pubmed/30682825
http://dx.doi.org/10.3390/biom9020041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406280/
https://www.ncbi.nlm.nih.gov/pubmed/30682825
http://dx.doi.org/10.3390/biom9020041

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