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Putative Mechanisms Underlying High Inhibitory Activities of Bimodular DNA Aptamers to Thrombin
Nucleic acid aptamers are prospective molecular recognizing elements. Similar to antibodies, aptamers are capable of providing specific recognition due to their spatial structure. However, the apparent simplicity of oligonucleotide folding is often elusive, as there is a balance between several conf...
Autores principales: | Zavyalova, Elena G., Legatova, Valeriia A., Alieva, Rugiya Sh., Zalevsky, Arthur O., Tashlitsky, Vadim N., Arutyunyan, Alexander M., Kopylov, Alexey M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406280/ https://www.ncbi.nlm.nih.gov/pubmed/30682825 http://dx.doi.org/10.3390/biom9020041 |
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