Casticin-Induced Inhibition of Cell Growth and Survival Are Mediated through the Dual Modulation of Akt/mTOR Signaling Cascade

The Akt/mTOR signaling cascade is a critical pathway involved in various physiological and pathological conditions, including regulation of cell proliferation, survival, invasion, and angiogenesis. In the present study, we investigated the anti-neoplastic effects of casticin (CTC), identified from t...

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Detalles Bibliográficos
Autores principales: Lee, Jong Hyun, Kim, Chulwon, Um, Jae-Young, Sethi, Gautam, Ahn, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406334/
https://www.ncbi.nlm.nih.gov/pubmed/30813295
http://dx.doi.org/10.3390/cancers11020254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406334/
https://www.ncbi.nlm.nih.gov/pubmed/30813295
http://dx.doi.org/10.3390/cancers11020254

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