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Casticin-Induced Inhibition of Cell Growth and Survival Are Mediated through the Dual Modulation of Akt/mTOR Signaling Cascade
The Akt/mTOR signaling cascade is a critical pathway involved in various physiological and pathological conditions, including regulation of cell proliferation, survival, invasion, and angiogenesis. In the present study, we investigated the anti-neoplastic effects of casticin (CTC), identified from t...
Autores principales: | Lee, Jong Hyun, Kim, Chulwon, Um, Jae-Young, Sethi, Gautam, Ahn, Kwang Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406334/ https://www.ncbi.nlm.nih.gov/pubmed/30813295 http://dx.doi.org/10.3390/cancers11020254 |
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