VAS2870 Inhibits Histamine-Induced Calcium Signaling and vWF Secretion in Human Umbilical Vein Endothelial Cells

In this study, we investigated the effects of NAD(P)H oxidase (NOX) inhibitor VAS2870 (3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine) on the histamine-induced elevation of free cytoplasmic calcium concentration ([Ca(2+)](i)) and the secretion of von Willebrand factor (vWF) in human...

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Detalles Bibliográficos
Autores principales: Avdonin, Pavel V., Rybakova, Elena Yu., Avdonin, Piotr P., Trufanov, Sergei K., Mironova, Galina Yu., Tsitrina, Alexandra A., Goncharov, Nikolay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406370/
https://www.ncbi.nlm.nih.gov/pubmed/30813397
http://dx.doi.org/10.3390/cells8020196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406370/
https://www.ncbi.nlm.nih.gov/pubmed/30813397
http://dx.doi.org/10.3390/cells8020196

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