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Overexpression of CDC42SE1 in A431 Cells Reduced Cell Proliferation by Inhibiting the Akt Pathway

Cell division cycle 42 (CDC42), a small Rho GTPase, plays a critical role in many cellular processes, including cell proliferation and survival. CDC42 interacts with the CRIB (Cdc42- and Rac-interactive binding) domain of CDC42SE1, a small effector protein of 9 kDa. We found that the expression of C...

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Detalles Bibliográficos
Autores principales: Kalailingam, Pazhanichamy, Tan, Hui Bing, Pan, Jiun Yit, Tan, Suat Hoon, Thanabalu, Thirumaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406378/
https://www.ncbi.nlm.nih.gov/pubmed/30717410
http://dx.doi.org/10.3390/cells8020117