Zoledronic Acid Modulation of TRPV1 Channel Currents in Osteoblast Cell Line and Native Rat and Mouse Bone Marrow-Derived Osteoblasts: Cell Proliferation and Mineralization Effect

Bisphosphonates (BPs) reduce bone pain and fractures by balancing the osteoblast/osteoclast ratio. The behavior of ion channels in the presence of BPs is not known. To investigate this, the effect of zoledronic acid BP (ZOL) (3 × 10(−8) to 5 × 10(−4) M) treatment, on ion channels, cell proliferation...

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Detalles Bibliográficos
Autores principales: Scala, Rosa, Maqoud, Fatima, Angelelli, Mariacristina, Latorre, Ramon, Perrone, Maria Grazia, Scilimati, Antonio, Tricarico, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406412/
https://www.ncbi.nlm.nih.gov/pubmed/30754651
http://dx.doi.org/10.3390/cancers11020206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406412/
https://www.ncbi.nlm.nih.gov/pubmed/30754651
http://dx.doi.org/10.3390/cancers11020206

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