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Switching on Endogenous Metal Binding Proteins in Parkinson’s Disease

The formation of cytotoxic intracellular protein aggregates is a pathological signature of multiple neurodegenerative diseases. The principle aggregating protein in Parkinson’s disease (PD) and atypical Parkinson’s diseases is α-synuclein (α-syn), which occurs in neural cytoplasmic inclusions. Sever...

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Detalles Bibliográficos
Autores principales: McLeary, Fleur A., Rcom-H’cheo-Gauthier, Alexandre N., Goulding, Michael, Radford, Rowan A. W., Okita, Yuho, Faller, Peter, Chung, Roger S., Pountney, Dean L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406413/
https://www.ncbi.nlm.nih.gov/pubmed/30791479
http://dx.doi.org/10.3390/cells8020179