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Liver Kinase B1—A Potential Therapeutic Target in Hormone-Sensitive Breast Cancer in Older Women

Background: The role of liver kinase B1 (LKB1), a serine/threonine kinase, has been described in the development of PeutzJagher’s syndrome, where a proportion (~45%) of patients have developed breast cancer in their lifetime. Cell line studies have linked LKB1 with oestrogen receptors (ER) and with...

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Detalles Bibliográficos
Autores principales: Syed, Binafsha Manzoor, Green, Andrew R, Morgan, David A L, Ellis, Ian O, Cheung, Kwok-Leung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406422/
https://www.ncbi.nlm.nih.gov/pubmed/30696074
http://dx.doi.org/10.3390/cancers11020149