High-Throughput Screening Identified Compounds Sensitizing Tumor Cells to Glucose Starvation in Culture and VEGF Inhibitors In Vivo

Tumor cells utilize glucose to fuel their anabolic needs, including rapid proliferation. However, due to defective vasculature and increased glucose uptake, tumor cells must overcome glucose deprivation. Accordingly, tumor cells depend on cellular pathways promoting survival under such conditions. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Marciano, Ran, Prasad, Manu, Ievy, Tal, Tzadok, Sapir, Leprivier, Gabriel, Elkabets, Moshe, Rotblat, Barak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406438/
https://www.ncbi.nlm.nih.gov/pubmed/30704052
http://dx.doi.org/10.3390/cancers11020156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406438/
https://www.ncbi.nlm.nih.gov/pubmed/30704052
http://dx.doi.org/10.3390/cancers11020156

Ejemplares similares