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Lung Tumorigenesis Alters the Expression of Slit2-exon15 Splicing Variants in Tumor Microenvironment

Slit2 expression is downregulated in various cancers, including lung cancer. We identified two Slit2 splicing variants at exon15—Slit2-WT and Slit2-ΔE15. In the RT-PCR analyses, the Slit2-WT isoform was predominantly expressed in all the lung cancer specimens and in their normal lung counterparts, w...

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Detalles Bibliográficos
Autores principales: Wu, Ming-Fang, Chuang, Cheng-Yen, Lin, Pinpin, Chen, Wei-Ting, Su, Shang-Er, Liao, Chen-Yi, Jan, Ming-Shiou, Chang, Jinghua Tsai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406468/
https://www.ncbi.nlm.nih.gov/pubmed/30717252
http://dx.doi.org/10.3390/cancers11020166