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The Nuclear Lamina as an Organizer of Chromosome Architecture

The nuclear lamina (NL) is a meshwork of lamins and lamin-associated proteins adjoining the inner side of the nuclear envelope. In early embryonic cells, the NL mainly suppresses background transcription, whereas, in differentiated cell types, its disruption affects gene expression more severely. No...

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Detalles Bibliográficos
Autores principales: Shevelyov, Yuri Y., Ulianov, Sergey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406483/
https://www.ncbi.nlm.nih.gov/pubmed/30744037
http://dx.doi.org/10.3390/cells8020136