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Impairment of Motor Function Correlates with Neurometabolite and Brain Iron Alterations in Parkinson’s Disease

We took advantage of magnetic resonance imaging (MRI) and spectroscopy (MRS) as non-invasive methods to quantify brain iron and neurometabolites, which were analyzed along with other predictors of motor dysfunction in Parkinson’s disease (PD). Tapping hits, tremor amplitude, and the scores derived f...

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Detalles Bibliográficos
Autores principales: Pesch, Beate, Casjens, Swaantje, Woitalla, Dirk, Dharmadhikari, Shalmali, Edmondson, David A., Zella, Maria Angela Samis, Lehnert, Martin, Lotz, Anne, Herrmann, Lennard, Muhlack, Siegfried, Kraus, Peter, Yeh, Chien-Lin, Glaubitz, Benjamin, Schmidt-Wilcke, Tobias, Gold, Ralf, van Thriel, Christoph, Brüning, Thomas, Tönges, Lars, Dydak, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406520/
https://www.ncbi.nlm.nih.gov/pubmed/30699914
http://dx.doi.org/10.3390/cells8020096