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A Biophysical Approach to the Identification of Novel ApoE Chemical Probes

Alzheimer’s disease (AD) is the most common type of dementia and, after age, the greatest risk factor for developing AD is the allelic variation of apolipoprotein E (ApoE), with homozygote carriers of the ApoE4 allele having an up to 12-fold greater risk of developing AD than noncarriers. Apolipopro...

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Detalles Bibliográficos
Autores principales: Kraft, Lucas, Serpell, Louise C., Atack, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406525/
https://www.ncbi.nlm.nih.gov/pubmed/30700058
http://dx.doi.org/10.3390/biom9020048