Cargando…
A Biophysical Approach to the Identification of Novel ApoE Chemical Probes
Alzheimer’s disease (AD) is the most common type of dementia and, after age, the greatest risk factor for developing AD is the allelic variation of apolipoprotein E (ApoE), with homozygote carriers of the ApoE4 allele having an up to 12-fold greater risk of developing AD than noncarriers. Apolipopro...
Autores principales: | Kraft, Lucas, Serpell, Louise C., Atack, John R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406525/ https://www.ncbi.nlm.nih.gov/pubmed/30700058 http://dx.doi.org/10.3390/biom9020048 |
Ejemplares similares
-
The Molecular Basis for Apolipoprotein E4 as the Major Risk Factor for Late-Onset Alzheimer's Disease
por: Raulin, Ana-Caroline, et al.
Publicado: (2019) -
How radiation influences atherosclerotic plaque development: a biophysical approach in ApoE ¯/¯ mice
por: Kloosterman, Astrid, et al.
Publicado: (2017) -
Biophysical Analyses for Probing Glycan-Protein Interactions
por: Nagae, Masamichi, et al.
Publicado: (2018) -
Biophysical
Characterization of Fluorotyrosine Probes
Site-Specifically Incorporated into Enzymes: E. coli Ribonucleotide Reductase As an Example
por: Oyala, Paul H., et al.
Publicado: (2016) -
ApoE and apoE receptors in brain lipid metabolism and AD
por: Bu, Guojun
Publicado: (2012)