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Contrasting Patterns of Rapid Molecular Evolution within the p53 Network across Mammal and Sauropsid Lineages

Cancer is a threat to multicellular organisms, yet the molecular evolution of pathways that prevent the accumulation of genetic damage has been largely unexplored. The p53 network regulates how cells respond to DNA-damaging stressors. We know little about p53 network molecular evolution as a whole....

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Detalles Bibliográficos
Autores principales: Passow, Courtney N, Bronikowski, Anne M, Blackmon, Heath, Parsai, Shikha, Schwartz, Tonia S, McGaugh, Suzanne E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406535/
https://www.ncbi.nlm.nih.gov/pubmed/30668691
http://dx.doi.org/10.1093/gbe/evy273