Saturated Fatty Acid Activates T Cell Inflammation Through a Nicotinamide Nucleotide Transhydrogenase (NNT)-Dependent Mechanism

Circulating fatty acids (FAs) increase with obesity and can drive mitochondrial damage and inflammation. Nicotinamide nucleotide transhydrogenase (NNT) is a mitochondrial protein that positively regulates nicotinamide adenine dinucleotide phosphate (NADPH), a key mediator of energy transduction and...

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Detalles Bibliográficos
Autores principales: McCambridge, Grace, Agrawal, Madhur, Keady, Alanna, Kern, Philip A., Hasturk, Hatice, Nikolajczyk, Barbara S., Bharath, Leena P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406569/
https://www.ncbi.nlm.nih.gov/pubmed/30823587
http://dx.doi.org/10.3390/biom9020079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406569/
https://www.ncbi.nlm.nih.gov/pubmed/30823587
http://dx.doi.org/10.3390/biom9020079

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