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Immunomagnetic-Enriched Subpopulations of Melanoma Circulating Tumour Cells (CTCs) Exhibit Distinct Transcriptome Profiles

Cutaneous melanoma circulating tumour cells (CTCs) are phenotypically and molecularly heterogeneous. We profiled the gene expression of CTC subpopulations immunomagnetic-captured by targeting either the melanoma-associated marker, MCSP, or the melanoma-initiating marker, ABCB5. Firstly, the expressi...

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Detalles Bibliográficos
Autores principales: Aya-Bonilla, Carlos, Gray, Elin S., Manikandan, Jayapal, Freeman, James B., Zaenker, Pauline, Reid, Anna L., Khattak, Muhammad A., Frank, Markus H., Millward, Michael, Ziman, Mel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406574/
https://www.ncbi.nlm.nih.gov/pubmed/30769764
http://dx.doi.org/10.3390/cancers11020157