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Investigating the Role of Everolimus in mTOR Inhibition and Autophagy Promotion as a Potential Host-Directed Therapeutic Target in Mycobacterium tuberculosis Infection

Tuberculosis (TB) is a serious infectious disease caused by the pathogen Mycobacterium tuberculosis (Mtb). The current therapy consists of a combination of antibiotics over the course of four months. Current treatment protocols run into problems due to the growing antibiotic resistance of Mtb and po...

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Detalles Bibliográficos
Autores principales: Cerni, Stephen, Shafer, Dylan, To, Kimberly, Venketaraman, Vishwanath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406581/
https://www.ncbi.nlm.nih.gov/pubmed/30754665
http://dx.doi.org/10.3390/jcm8020232