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Host-Cell Type Dependent Features of Recombinant Human Aquaporin-4 Orthogonal Arrays of Particles—New Insights for Structural and Functional Studies

The CNS plasma-membrane water channel aquaporin-4 (AQP4) is expressed as two major isoforms able to aggregate into supramolecular assemblies known as ‘orthogonal arrays of particles’ (OAPs). OAP subnanometric features are largely unknown mainly because a method for the expression, isolation, and cry...

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Detalles Bibliográficos
Autores principales: Pisani, Francesco, Simone, Laura, Mola, Maria Grazia, De Bellis, Manuela, Mastrapasqua, Maria, Ruggieri, Maddalena, Trojano, Maria, Nicchia, Grazia Paola, Svelto, Maria, Frigeri, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406603/
https://www.ncbi.nlm.nih.gov/pubmed/30717425
http://dx.doi.org/10.3390/cells8020119