Detecting Chromosome Instability in Cancer: Approaches to Resolve Cell-to-Cell Heterogeneity

Chromosome instability (CIN) is defined as an increased rate of chromosome gains and losses that manifests as cell-to-cell karyotypic heterogeneity and drives cancer initiation and evolution. Current research efforts are aimed at identifying the etiological origins of CIN, establishing its roles in...

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Detalles Bibliográficos
Autores principales: Lepage, Chloe C., Morden, Claire R., Palmer, Michaela C. L., Nachtigal, Mark W., McManus, Kirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406658/
https://www.ncbi.nlm.nih.gov/pubmed/30781398
http://dx.doi.org/10.3390/cancers11020226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406658/
https://www.ncbi.nlm.nih.gov/pubmed/30781398
http://dx.doi.org/10.3390/cancers11020226

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