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Detecting Chromosome Instability in Cancer: Approaches to Resolve Cell-to-Cell Heterogeneity
Chromosome instability (CIN) is defined as an increased rate of chromosome gains and losses that manifests as cell-to-cell karyotypic heterogeneity and drives cancer initiation and evolution. Current research efforts are aimed at identifying the etiological origins of CIN, establishing its roles in...
Autores principales: | Lepage, Chloe C., Morden, Claire R., Palmer, Michaela C. L., Nachtigal, Mark W., McManus, Kirk J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406658/ https://www.ncbi.nlm.nih.gov/pubmed/30781398 http://dx.doi.org/10.3390/cancers11020226 |
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