Targeting Glioblastoma Stem Cells with 2-Deoxy-D-Glucose (2-DG) Potentiates Radiation-Induced Unfolded Protein Response (UPR)

Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults, and despite optimized treatment options, median survival remains dismal. Contemporary evidence suggests disease recurrence results from expansion of a robustly radioresistant subset of GBM progenitor cells, termed GB...

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Detalles Bibliográficos
Autores principales: Shah, Sumedh S., Rodriguez, Gregor A., Musick, Alexis, Walters, Winston M., de Cordoba, Nicolas, Barbarite, Eric, Marlow, Megan M., Marples, Brian, Prince, Jeffrey S., Komotar, Ricardo J., Vanni, Steven, Graham, Regina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406669/
https://www.ncbi.nlm.nih.gov/pubmed/30709011
http://dx.doi.org/10.3390/cancers11020159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406669/
https://www.ncbi.nlm.nih.gov/pubmed/30709011
http://dx.doi.org/10.3390/cancers11020159

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