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Impaired CENP-E Function Renders Large Chromosomes More Vulnerable to Congression Failure

It has recently emerged that human chromosomes vary between one another in terms of features that impact their behaviour during impaired chromosome segregation, leading to non-random aneuploidy in the daughter cell population. During the process of chromosome congression to the metaphase plate, chro...

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Detalles Bibliográficos
Autores principales: Tovini, Laura, McClelland, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406671/
https://www.ncbi.nlm.nih.gov/pubmed/30691136
http://dx.doi.org/10.3390/biom9020044