Apolipoprotein E4 Alters Astrocyte Fatty Acid Metabolism and Lipid Droplet Formation

Lipid droplets (LDs) serve as energy rich reservoirs and have been associated with apolipoprotein E (APOE) and neurodegeneration. The E4 allele of APOE (E4) is the strongest genetic risk factor for the development of late onset Alzheimer’s disease (AD). Since both E4 carriers and individuals with AD...

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Detalles Bibliográficos
Autores principales: Farmer, Brandon C., Kluemper, Jude, Johnson, Lance A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406677/
https://www.ncbi.nlm.nih.gov/pubmed/30791549
http://dx.doi.org/10.3390/cells8020182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406677/
https://www.ncbi.nlm.nih.gov/pubmed/30791549
http://dx.doi.org/10.3390/cells8020182

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