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PDL-1 Antibody Drug Conjugate for Selective Chemo-Guided Immune Modulation of Cancer
Targeting immune checkpoint molecules such as programmed death ligand-1 (PDL1) is an emerging strategy for anti-cancer therapy. However, transient expression of PDL1 and difficulty in tumor stroma penetration has limited the utility of anti-PDL1 therapy. To overcome these limitations, we report a ne...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406713/ https://www.ncbi.nlm.nih.gov/pubmed/30781490 http://dx.doi.org/10.3390/cancers11020232 |