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Retroelement—Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution

Background: Retroelements (REs) are transposable elements occupying ~40% of the human genome that can regulate genes by providing transcription factor binding sites (TFBS). RE-linked TFBS profile can serve as a marker of gene transcriptional regulation evolution. This approach allows for interrogati...

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Detalles Bibliográficos
Autores principales: Nikitin, Daniil, Garazha, Andrew, Sorokin, Maxim, Penzar, Dmitry, Tkachev, Victor, Markov, Alexander, Gaifullin, Nurshat, Borger, Pieter, Poltorak, Alexander, Buzdin, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406739/
https://www.ncbi.nlm.nih.gov/pubmed/30736359
http://dx.doi.org/10.3390/cells8020130