Cargando…

Retroelement—Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution

Background: Retroelements (REs) are transposable elements occupying ~40% of the human genome that can regulate genes by providing transcription factor binding sites (TFBS). RE-linked TFBS profile can serve as a marker of gene transcriptional regulation evolution. This approach allows for interrogati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nikitin, Daniil, Garazha, Andrew, Sorokin, Maxim, Penzar, Dmitry, Tkachev, Victor, Markov, Alexander, Gaifullin, Nurshat, Borger, Pieter, Poltorak, Alexander, Buzdin, Anton
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406739/ https://www.ncbi.nlm.nih.gov/pubmed/30736359 http://dx.doi.org/10.3390/cells8020130

Ejemplares similares

Correction: Nikitin, D., et al. Retroelement—Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution. Cells 2019, 8, 130
por: Nikitin, Daniil, et al.
Publicado: (2019)

Profiling of Human Molecular Pathways Affected by Retrotransposons at the Level of Regulation by Transcription Factor Proteins
por: Nikitin, Daniil, et al.
Publicado: (2018)

Retroelement-Linked H3K4me1 Histone Tags Uncover Regulatory Evolution Trends of Gene Enhancers and Feature Quickly Evolving Molecular Processes in Human Physiology
por: Nikitin, Daniil, et al.
Publicado: (2019)

Algorithmically Reconstructed Molecular Pathways as the New Generation of Prognostic Molecular Biomarkers in Human Solid Cancers
por: Zolotovskaia, Marianna, et al.
Publicado: (2023)

Machine Learning Applicability for Classification of PAD/VCD Chemotherapy Response Using 53 Multiple Myeloma RNA Sequencing Profiles
por: Borisov, Nicolas, et al.
Publicado: (2021)

Gene Expression-Based Signature Can Predict Sorafenib Response in Kidney Cancer
por: Gudkov, Alexander, et al.
Publicado: (2022)

RNA Sequencing in Comparison to Immunohistochemistry for Measuring Cancer Biomarkers in Breast Cancer and Lung Cancer Specimens
por: Sorokin, Maxim, et al.
Publicado: (2020)

Cancer gene expression profiles associated with clinical outcomes to chemotherapy treatments
por: Borisov, Nicolas, et al.
Publicado: (2020)

Gene expression and molecular pathway activation signatures of MYCN-amplified neuroblastomas
por: Petrov, Ivan, et al.
Publicado: (2017)

Atlas of RNA sequencing profiles for normal human tissues
por: Suntsova, Maria, et al.
Publicado: (2019)

Flexible Data Trimming Improves Performance of Global Machine Learning Methods in Omics-Based Personalized Oncology
por: Tkachev, Victor, et al.
Publicado: (2020)

DNA repair pathway activation features in follicular and papillary thyroid tumors, interrogated using 95 experimental RNA sequencing profiles
por: Vladimirova, Uliana, et al.
Publicado: (2021)

Human Blood Serum Can Diminish EGFR-Targeted Inhibition of Squamous Carcinoma Cell Growth through Reactivation of MAPK and EGFR Pathways
por: Kamashev, Dmitri, et al.
Publicado: (2023)

FLOating-Window Projective Separator (FloWPS): A Data Trimming Tool for Support Vector Machines (SVM) to Improve Robustness of the Classifier
por: Tkachev, Victor, et al.
Publicado: (2019)

Intratumoral Heterogeneity and Longitudinal Changes in Gene Expression Predict Differential Drug Sensitivity in Newly Diagnosed and Recurrent Glioblastoma
por: Kim, Ella L., et al.
Publicado: (2020)

RNA sequencing profiles and diagnostic signatures linked with response to ramucirumab in gastric cancer
por: Sorokin, Maxim, et al.
Publicado: (2020)

Shambhala: a platform-agnostic data harmonizer for gene expression data
por: Borisov, Nicolas, et al.
Publicado: (2019)

Molecular pathway activation features linked with transition from normal skin to primary and metastatic melanomas in human
por: Shepelin, Denis, et al.
Publicado: (2015)

H3K4me3, H3K9ac, H3K27ac, H3K27me3 and H3K9me3 Histone Tags Suggest Distinct Regulatory Evolution of Open and Condensed Chromatin Landmarks
por: Igolkina, Anna A., et al.
Publicado: (2019)

Algorithmic Annotation of Functional Roles for Components of 3,044 Human Molecular Pathways
por: Sorokin, Maxim, et al.
Publicado: (2021)

Personalized targeted therapy prescription in colorectal cancer using algorithmic analysis of RNA sequencing data
por: Sorokin, Maxim, et al.
Publicado: (2022)

Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs
por: Zolotovskaia, Marianna A., et al.
Publicado: (2019)

A systematic experimental evaluation of microRNA markers of human bladder cancer
por: Zabolotneva, Anastasia A., et al.
Publicado: (2013)

New bioinformatic tool for quick identification of functionally relevant endogenous retroviral inserts in human genome
por: Garazha, Andrew, et al.
Publicado: (2015)

A method for predicting target drug efficiency in cancer based on the analysis of signaling pathway activation
por: Artemov, Artem, et al.
Publicado: (2015)

Better Agreement of Human Transcriptomic and Proteomic Cancer Expression Data at the Molecular Pathway Activation Level
por: Raevskiy, Mikhail, et al.
Publicado: (2022)

Uniformly shaped harmonization combines human transcriptomic data from different platforms while retaining their biological properties and differential gene expression patterns
por: Borisov, Nicolas, et al.
Publicado: (2023)

High FREM2 Gene and Protein Expression Are Associated with Favorable Prognosis of IDH-WT Glioblastomas
por: Jovčevska, Ivana, et al.
Publicado: (2019)

Mutation Enrichment and Transcriptomic Activation Signatures of 419 Molecular Pathways in Cancer
por: Zolotovskaia, Marianna A., et al.
Publicado: (2020)

Large-scale assessment of pros and cons of autopsy-derived or tumor-matched tissues as the norms for gene expression analysis in cancers
por: Sorokin, Maksim, et al.
Publicado: (2023)

A Review of Recent Studies on the Effects of SARS-CoV-2 Infection and SARS-CoV-2 Vaccines on Male Reproductive Health
por: Adamyan, Leila, et al.
Publicado: (2022)

RNA Sequencing-Based Identification of Ganglioside GD2-Positive Cancer Phenotype
por: Sorokin, Maxim, et al.
Publicado: (2020)

Case of multifocal glioblastoma with four fusion transcripts of ALK, FGFR2, NTRK2, and NTRK3 genes stresses the need for tumor tissue multisampling for transcriptomic analysis
por: Samii, Amir, et al.
Publicado: (2021)

Experimental and Meta-Analytic Validation of RNA Sequencing Signatures for Predicting Status of Microsatellite Instability
por: Sorokin, Maksim, et al.
Publicado: (2021)

OncoboxPD: human 51 672 molecular pathways database with tools for activity calculating and visualization
por: Zolotovskaia, Marianna A., et al.
Publicado: (2022)

Large-Scale Profiling of Signaling Pathways Reveals a Distinct Demarcation between Normal and Extended Liver Resection
por: Borger, Pieter, et al.
Publicado: (2020)

Molecular pathway activation features of pediatric acute myeloid leukemia (AML) and acute lymphoblast leukemia (ALL) cells
por: Petrov, Ivan, et al.
Publicado: (2016)

Functional Properties of Circulating Exosomes Mediated by Surface-Attached Plasma Proteins
por: Shtam, Tatiana, et al.
Publicado: (2018)

Endogenous retroelements and autoimmunity
por: Stetson, Daniel B
Publicado: (2009)

Retroviruses, retroelements and their restrictions
por: Koito, Atsushi, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_vtntton1ntr7ei2eujspc7h9hl