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Characterization of SIRT1/DNMTs Functions and LINE-1 Methylation in Patients with Age-Related Macular Degeneration

Previous studies proposed the application of DNA methylation signatures as clinical biomarkers of age-related macular degeneration (AMD). However, the characterization of Long Interspersed Nuclear Element-1 (LINE-1) methylation levels—a surrogate marker of global DNA methylation—in AMD patients has...

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Detalles Bibliográficos
Autores principales: Maugeri, Andrea, Barchitta, Martina, Fallico, Matteo, Castellino, Niccolò, Reibaldi, Michele, Agodi, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406755/
https://www.ncbi.nlm.nih.gov/pubmed/30717113
http://dx.doi.org/10.3390/jcm8020159