Developing Targeted Therapies That Exploit Aberrant Histone Ubiquitination in Cancer

Histone ubiquitination is a critical epigenetic mechanism regulating DNA-driven processes such as gene transcription and DNA damage repair. Importantly, the cellular machinery regulating histone ubiquitination is frequently altered in cancers. Moreover, aberrant histone ubiquitination can drive onco...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeusset, Lucile M-P, McManus, Kirk J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406838/
https://www.ncbi.nlm.nih.gov/pubmed/30781493
http://dx.doi.org/10.3390/cells8020165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406838/
https://www.ncbi.nlm.nih.gov/pubmed/30781493
http://dx.doi.org/10.3390/cells8020165

Ejemplares similares