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Developing Targeted Therapies That Exploit Aberrant Histone Ubiquitination in Cancer

Histone ubiquitination is a critical epigenetic mechanism regulating DNA-driven processes such as gene transcription and DNA damage repair. Importantly, the cellular machinery regulating histone ubiquitination is frequently altered in cancers. Moreover, aberrant histone ubiquitination can drive onco...

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Detalles Bibliográficos
Autores principales:	Jeusset, Lucile M-P, McManus, Kirk J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406838/ https://www.ncbi.nlm.nih.gov/pubmed/30781493 http://dx.doi.org/10.3390/cells8020165

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