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The Importance of the Hedgehog Signaling Pathway in Tumorigenesis of Spinal and Cranial Chordoma

Chordomas is rare malignant bone tumors thought to arise from remnants of embryonic notochord along the spine, frequently at the skull base and sacrum. Although chordoma is slow growing tumors, while are extremely recurrent, and aggressive, as well as the rate of prognosis remains poorly. Radical su...

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Detalles Bibliográficos
Autores principales: Akhavan-Sigari, Reza, Schulz-Schaeffer, Walter, Angelika Harcej, Amanda, Rohde, Veit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406847/
https://www.ncbi.nlm.nih.gov/pubmed/30769952
http://dx.doi.org/10.3390/jcm8020248