Nevoid Basal Cell Carcinoma Syndrome: PTCH1 Mutation Profile and Expression of Genes Involved in the Hedgehog Pathway in Argentinian Patients

Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder characterized by multiple basal cell carcinomas (BCC), mainly caused by PTCH1 gene mutations. Our current study aimed to establish (1) PTCH1 germinal and somatic mutational status, (2) component and Hedgehog (HH) pathway...

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Detalles Bibliográficos
Autores principales: Martinez, Maria Florencia, Romano, Maria Vanesa, Martinez, Alfredo Pedro, González, Abel, Muchnik, Carolina, Stengel, Fernando Miguel, Mazzuoccolo, Luis Daniel, Azurmendi, Pablo Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406887/
https://www.ncbi.nlm.nih.gov/pubmed/30754660
http://dx.doi.org/10.3390/cells8020144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406887/
https://www.ncbi.nlm.nih.gov/pubmed/30754660
http://dx.doi.org/10.3390/cells8020144

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